Wuhan Hhd Supply Neratinib Powder Pharmaceutical Intermediate Neratinib (HKI-272) CAS 698387-09-6

• Powder: Yes
• Customized: Non-Customized
• Suitable for: Adult
• Purity: >98%
• Color: White
• Grade: Pharmaceutical Grade
• Model NO.: CAS 698387-09-6
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan HHD Supply Neratinib Powder Pharmaceutical Intermediate Neratinib (HKI-272) CAS 698387-09-6

 

Basic information:

Density	1.3±0.1 g/cm3
Boiling Point	757.0±60.0 °C at 760 mmHg
Molecular Formula	C30H29ClN6O3
Molecular Weight	557.043
Flash Point	411.6±32.9 °C
Exact Mass	556.198975
PSA	112.40000
LogP	5.46
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.667

Description:

Neratinib is an irreversible epidermal grow factor receptor (EGFR) inhibitor. It is a small molecule tyrosine kinase inhibitor targeting HER2 and HER1 after lapatinib. It is an irreversible pan erbB receptor tyrosine kinase inhibitor. It can selectively inhibit HER-1 and HER-2 (IC50 = 92 nmol / L and 59 nmol / L, respectively). Clinical studies have shown that it has obvious therapeutic effect on non-small cell lung cancer, colon cancer and breast cancer.