| Powder: | Yes |
|---|---|
| Customized: | Non-Customized |
| Suitable for: | Elderly, Adult |
| Purity: | >98% |
| Free Base: | 1205548-04-4 |
| Hbr Salt: | 1205548-00-0 |
| Customization: |
|---|
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Audited Supplier Eutropoflavin (4'-Dimethylamino-7,8-dihydroxyflavone) is a synthetic flavone and selective small-molecule agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF), which was derived from structural modification of tropoflavin (7,8-DHF).Relative to tropoflavin, eutropoflavin possesses higher agonistic activity at TrkB, is significantly more potent than tropoflavin both in vitro and in vivo, and has a longer duration of action (peaking at 4 hours and "partially decaying" at 8~16 hours in rodents). The compound has been found to produce neuroprotective and neurogenic effects in the brain and spinal cord as well as antidepressant-like effects in animals
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Product Name |
4'-DMA-7,8-DHF |
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Other Name |
4'-Dimethylamino-7,8-dihydroxyflavone Hydrobromide |
|
CAS No. |
1205548-00-0 |
|
Appearance |
yellow powder |
|
Purity |
99% |
|
Storage |
Room temperature |
|
MF |
C17H15NO4 |
|
Shelf Life |
2 years |
| Grade | Enterprise standard |
How does 7,8 DHF Work
7,8-DHF mimics the effects of brain-derived neurotrophic factor (BDNF) in the brain by activating the tropomyosin-related kinase B (TrkB) receptors .
The therapeutic potential of BDNF is restricted due to its short half-life (less than 10 minutes) and its inability to cross the blood-brain barrier because of its large size. Unlike BDNF 7,8-DHF is able to penetrate the blood-brain barrier and enter the central nervous system (CNS) .
7,8-DHF also increases the production of Nrf2. Nrf2 increases antioxidants enzymes such as heme oxygenase 1 (HO-1) and also enzymes that repair DNA (8-oxoguanine DNA glycosylase-1 - OGG1)
Function
1) May Improve Memory and Learning
2) May Promote Brain Repair
7,8-DHF promoted the repair of damaged neurons .
3) May Be Neuroprotective
4) Has Antioxidant Effects
5) Has Anti-Inflammatory Effects
7,8-DHF decreases the release of inflammatory factors in brain cells by blocking NF-κB .
6) May Be Beneficial in Neurodegenerative and Neurodevelopmental Diseases
7) May Treat Depression
8) May Treat Addiction
9) May Combat Obesity
10) May Improve Blood Pressure
11) May Prevent Skin Cancer
7,8-DHF kills oral squamous cancer cells and skin cancer (melanoma) cells .
12) May Prevent Skin Aging
Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.
Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q3: Is there a discount?
A:Different quantity has different discount.
Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.
Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
Suppliers with verified business licenses
Audited Supplier 
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