Wuhan Hhd Supply Linagliptin CAS 668270-12-0 Ondero for Type 2 Diabetes

• Powder: Yes
• Customized: Non-Customized
• Certification: Enterprise Standards
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Model NO.: CAS 668270-12-0
• Color: White
• Grade: Pharmaceutical Grade
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan HHD Supply Linagliptin CAS 668270-12-0 Ondero for Type 2 Diabetes

Product Name: Linagliptin
Synonyms: linagliptin;8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione;(R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione;1H-Purine-2,6-dione, 8-((3R)-3-amino-1-piperidinyl)-7-(2-butynyl)-3,7-dihydro-3-methyl-1-((4-methyl-2-quinazolinyl)methyl)-;Bi 1356;Ondero;8-[(3R)-3-AMino-1-piperidinyl]-7-(2-butyn-1-yl)-3,7-dihydro-3-Methyl-1-[(4-Methyl-2-quinazolinyl)Methyl]-1H-purine-2,6-dione;8-[(3R)-3-AMino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-Methyl-1-[(4-Methyl-2-quinazolinyl)Methyl]-1H-purine-2,6-d
CAS: 668270-12-0
MF: C25H28N8O2
MW: 472.54
EINECS: 621-260-7

Melting point: 202ºC
Boiling point: 661.2±65.0 °C
Density: 1.39
Storage temp.: Store at RT
Appearance: Off-White Powder

Description:

Linagliptin shows modest oral bioavailability, and it is rapidly absorbed. The maximum plasma concentration at steady state is reached on average 1.5 hours after administration of linagliptin 5 mg, once daily . Linagliptin half-life is 131 hours. No relevant food effects were observed on the absorption profile of linagliptin. Unlike other DPP-4 inhibitors, linagliptin excretion is not performed by the kidneys, but rather through the enterohepatic system.

Uses:

A novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.