High Purity 99.6% Anti-Tumor Etoposide CAS 33419-42-0 Manufacturer and Exporter

• Certification: BRC, ISO, HACCP, in-House Standard
• Assay Method: HPLC-MS, UV
• Application Form: Injection, Tablet, Capsule
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Cordate Houttuynia
• Appearance: Solid
• Transport Package: Aluminum Foil Bag
• Specification: 100G/BAG 1KG/BAG
• Trademark: HENGHEDA
• Origin: China
• HS Code: 2932999099
• Production Capacity: 100kg/Quater

Product Description

Product Name	Etoposide
Appearance	White Crystalline Powder
CAS No	33419-42-0
MF	C29H32O13
Purity	99%
Description	An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor UsesA DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. Etoposide (VePesid) is a semisynthetic derivative of podophyllotoxin that is produced in the roots of the American mandrake, or May apple. Unlike podophyllotoxin and vinca alkaloids, etoposide does not bind to microtubules. It forms a complex with the enzyme topoisomerase II, which results in a single-strand breakage of DNA. It is most lethal to cells in the S- and G2-phases of the cell cycle. Drug resistance to etoposide is thought to be caused by decreased cellular drug accumulation.
Function	1) Etoposide is used as a form of chemotherapy for cancers such as Kaposi's sarcoma, Ewing's sarcoma,lung cancer, testicular cancer, lymphoma, nonlymphocytic leukemia, and glioblastoma multiforme. 2) It is often given in combination with other drugs (such as bleomycin in treating testicular cancer). 3) It is also sometimes used in a conditioning regimen prior to a bone marrow or blood stem cell transplant.