Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name
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Factory Supply Silodosin CAS 160970-54-7 bulk Silodosin Powder |
Appearance
|
WHITE Crystalline powder |
Assay
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99%min, 98.0% --101.0% |
Test
|
HPLC
|
Certificate
|
ISO 9001
|
CAS
|
160970-54-7 |
MF | C25H32F3N3O4 |
Storage Temperature |
Cool Dry Place
|
Silodosin is a kind of α- adrenergic receptor antagonists developed by Japanese Kissei pharmaceutical company. It has
a very good therapeutic efficacy on treating the dysuria related to benign prostatic hyperplasia. The selective effect on
urethra of Silodosin is 12 times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can
significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent inhibition bladder activity
excitation in the benign prostatic hypertrophy models of rats, and can also improve the pressure threshold of bladder
contraction. These data have suggested that, in addition to helping improve bladder function, silodosin is also effective
in alleviating the related symptoms associated with benign prostatic hypertrophy.
Compared with similar drugs such as prazosin and tamsulosin, silodosin has a high selectivity onn theα1A- receptors
located in the prostate and bladder neck, while having a low affinity to theα1B- and α1D-receptor. It can block
theα1A- receptors in these sites, and relax the smooth , and thus leading to the improvement of urinary flow rate
and the alleviation of BPH symptoms.
The selective binding to the α1A-receptor by silodosin has a higher selectivity compared to the binding to the
cardiovascular associated receptors α1B, thus maximizing the activity of the target organ as well as minimizing the
potential effect on blood pressure.
Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.
Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q3: Is there a discount?
A:Different quantity has different discount.
Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.
Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.