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Wuhan Hhd Supply PQ-29 Lab synthesis For Weight Loss 5-Amino-1mq
PQ-29 reduces post-traumatic neurodegeneration and saves motor function of traumatized rats. (A) The result of rat's brain immunoblotting analysis. Brain lysates were stained with anti-Hsp70 and anti-GAPDH antibodies on one, three or five days after an intraperitoneal of PQ-29. (B) The result of band intensity quantification from section A is presented. The histogram bars show the average normalized band intensity of Hsp70 quantified based on three independent experiments. (C) Rats were anesthetized and divided into four groups: TBI groups were traumatized, the other two groups were not. The PQ-29 groups were treated with intraperitoneal PQ-29 three times a week. DMSO was used as a vehicle. The beam walking test was employed to define the changes in locomotor function, as described in the text. The coefficient of slipping defines the height of the histogram bars. (D) The confocal microscopy data are presented. Rats' brains from different groups, as described in section A, were sliced and stained with 4′,6-diamidino-2-phenylindole (DAPI) (cyan) and Click-It TUNEL kit (red). The CA1 hippocampus field is shown. Scale bar 10 µ m. (E) The number of cell nuclei stained with DAPI was normalized to that in hippocampus of control animals and presented as histogram bars. For each group, no less than 500 cells were counted.
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