Wuhan Hhd Pharm Supply Everolimus Powder CAS 159351-69-6 for Immuno Suppressant

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Certification: ISO 9001, Enterprise Standards
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Color: White
• Grade: Pharmaceutical Grade
• Test Method: HPLC, Lcms, Hnmr
• COA: Available
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan Hhd Pharm Supply Everolimus Powder CAS 159351-69-6 for Immuno Suppressant

Product Name: Everolimus
Synonyms: Everolimus(mixture of isomers);Everolimus powder;CERTICAN; ZORTRESS; AFINITOR;Rapamycin, 42-O-(2-hydroxyethyl)-;Everolimus;Certican;CERTICAN(R);EveroliMus(RAD-001)
CAS: 159351-69-6
MF: C53H83NO14
MW: 958.232
EINECS: 621-003-9

Melting point: 96-97°C
Boiling point: 998.7±75.0 °C
Density: 1.18±0.1 g/cm3
Storage temp.: −20°C
Appearance: White Powder

Description:

Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology



Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.

Tacrolimus is also available:

Product Name:  Tacrolimus
CAS Number: 104987-11-3
Appearance: White or off-white crystalline powder
Molecular formula: C44H69NO12
Molecular weight:  804.018
Density: 1.19g/cm³
Melting point: 113 to 115 ºC
Boiling point: 871.7 ºC
Flash point: 481.0 ºC
Solubility:  DMSO: >3 mg/mL
Refractive index: 1.549
Storage condition: Sealed in dry,Store in freezer, under -20°C

Macrolide antibiotics. Immunosuppressants. The mechanism of action is the same as cyclosporin, mainly inhibiting the synthesis of interleukin-2. Rejection reaction for organ transplantation.
A macrolide that binds to FK506 binding protein (FKBP) to form a complex, thereby reducing peptidyl prolyl isomerase activity in T cells.

purpose:
Macrolide antibiotics. Immunosuppressants. The mechanism of action is the same as cyclosporin, mainly inhibiting the synthesis of interleukin-2. Rejection reaction for organ transplantation.
A macrolide that binds to FK506 binding protein (FKBP) to form a complex, thereby reducing peptidyl prolyl isomerase activity in T cells

 

 

 

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