| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
7,8-Dihydroxyflavone (7,8-DHF) is a potential nootropic that may improve overall brain health, mood, and cognitive function. It may also be of benefit for several neurodegenerative and neurodevelopmental disorders, as well as obesity and elevated blood pressure.
7,8-Dihydroxyflavone (7,8-DHF) is a flavone found in plants. It was discovered while searching for molecules that imitate the function of brain-derived neurotrophic factor (BDNF)
BDNF promotes the growth of neurons and synapses (synaptogenesis) and is very important for normal brain function. Lower amounts of BDNF are observed in diseases such as depression, Alzheimer's, Parkinson's, and Schizophrenia.
| CAS | 38183-03-8 |
| MF | C15H10O4 |
| Purity | 99% |
| MW | 254.24 |
| Appearance | yellow Crystalline Solid |
How does 7,8 DHF Work
7,8-DHF mimics the effects of brain-derived neurotrophic factor (BDNF) in the brain by activating the tropomyosin-related kinase B (TrkB) receptors .
The therapeutic potential of BDNF is restricted due to its short half-life (less than 10 minutes) and its inability to cross the blood-brain barrier because of its large size. Unlike BDNF 7,8-DHF is able to penetrate the blood-brain barrier and enter the central nervous system (CNS) .
7,8-DHF also increases the production of Nrf2. Nrf2 increases antioxidants enzymes such as heme oxygenase 1 (HO-1) and also enzymes that repair DNA (8-oxoguanine DNA glycosylase-1 - OGG1)
Function
1) May Improve Memory and Learning
2) May Promote Brain Repair
7,8-DHF promoted the repair of damaged neurons .
3) May Be Neuroprotective
4) Has Antioxidant Effects
5) Has Anti-Inflammatory Effects
7,8-DHF decreases the release of inflammatory factors in brain cells by blocking NF-κB .
6) May Be Beneficial in Neurodegenerative and Neurodevelopmental Diseases
7) May Treat Depression
8) May Treat Addiction
9) May Combat Obesity
10) May Improve Blood Pressure
11) May Prevent Skin Cancer
7,8-DHF kills oral squamous cancer cells and skin cancer (melanoma) cells .
12) May Prevent Skin Aging
){kind=link}