Safe Shipping 99% Hot Selling Mirabegron CAS 223673-61-8

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: HHD
• COA: Available
• Shelf Life: 4 Years
• Storage: Cool Dry Place
• Color: White
• Transport Package: Bag
• Specification: Customized
• Trademark: HHD
• Origin: Hubei
• Production Capacity: 50000 Pieces Per Year

Product Description

 

Basic Information

 

 

Product Name: Mirabegron
CAS: 223673-61-8
MF:C21H24N4O2S
MW:396.51
EINECS:800-126-3
MDL No.:MFCD11100356
Melting point:138-140°C
Boiling point:690.0±55.0 °C(Predicted)
Density 1.313
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka13.51±0.70(Predicted)
form Solid
color White to Pale Yellow
Purity: 99%
Package:  100g;1kg;5kg

Product Name:	Mirabegron
CAS:	223673-61-8
MF:	C21H24N4O2S
MW:	396.51
EINECS:	800-126-3
Mol File:	223673-61-8.mol

Description:

Mirabegron is for the treatment of urgency, urinary frequency, and urinary urge urinary incontinence associated with overactive bladder (OAB). Mirabegron is synthesized by coupling 4-nitrophenethyl amine to (R)-2-hydroxy-2-phenylacetic acid. The resulting amide is reduced to an amine. The nitro group is then reduced and the resulting is coupled to 2-(2-aminothiazol-4-yl) acetic acid to give mirabegron. Mirabegron has an EC50 of 22 nM (intrinsic activity=0.8) for β3-AR with no detectable activity for β1- andβ2-AR (EC50>10,000 nM). In an anesthetized rat rhythmic bladder contraction model in which bladder contractions are induced by saline, mirabegron at 3 mg/kg iv decreased the frequency of rhythmic bladder contraction without suppressing contraction amplitude. These data suggest that the activation of β3-AR increases bladder capacity without influencing the frequency of bladder contraction.

Application

1.Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
2.Uses for A potent bladder relaxant compound
3.Uses for Potent bladder relaxant and reagent for diabetes remedy.;Labeled Mirabegron, intended for use as an internal standard for the quantification of Mirabegron by GC- or LC-mass spectrometry.

 

Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.

Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?
A:Different quantity has different discount.

Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.

Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.