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English name: CANDESARTAN CILEXETIL Uses: Antihypertensive pharmaceutical raw materials Molecular formula: C33H34N6O6 CAS number: 145040-37-5 State/Appearance: White solid powder Packaging: The inner packaging is a medical polyethylene plastic bag, and the outer packaging is a cardboard drum.
5-25kg
USD 500/KG
T/T advance
25-50kg
USD 450/KG
50%+50%
Candesartan cilexetil is a kind of prodrug being hydrolyzed to candesartan during absorption from the gastrointestinal tract. It appears as a white or off-white powder with a molecular weight of 610.67. It is soluble in meth-anol but insoluble in water. It is a kind of selective AT1 subtype angiotensin II receptor antagonist, mainly used for the treatment of hypertension and heart failure. Candesartan cilexetil takes effects through selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland, further blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Therefore, its mode of action is not through interfering with the pathways for angiotensin II synthesis.