Product Name: |
Hyodeoxycholic acid |
Synonyms: |
5BETA-CHOLAN-24 OIC ACID-3ALPHA,6ALPHA-DIOL;5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA-DIOL;3ALPHA, 6ALPHA-DIHYDROXY-5BETA-CHOLANIC ACID;3-ALPHA,6-ALPHA-DIHYDROXY-5-ALPHA-CHOLAN-24-OIC ACID;3ALPHA,6ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID;ALPHA-HYODESOXYCHOLIC ACID;HYODESOXYCHOLIC ACID;HYODEOXYCHOLANIC ACID |
CAS: |
83-49-8 |
MF: |
C24H40O4 |
MW: |
392.57 |
EINECS: |
201-483-2 |
Hyodeoxycholic acid, also known as 3α,6α-Dihydroxy-5β-cholan-24-oic acid or HDCA, is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria. It differs from deoxycholic acid in that the 6α-hydroxyl is in the 12 position in the former. The 6α-hydroxyl group makes HDCA a hydrophilic acid, a property it shares with hyocholic acid. HDCA is present in mammalian species in different proportions. It is the main acid constituent of hog bile, and for this reason it was used industrially as precursor for steroid synthesis before total synthesis became practical.
It is suitable for type Ia and IB hyperlipidemia and atherosclerosis. It has certain antibacterial effect on pertussis bacillus, Diphtheria Bacillus and Staphylococcus aureus. It is also suitable for cholangitis, cholecystitis, cholelithiasis and other non obstructive cholestasis. It can accelerate the excretion of gallbladder contrast agent from the liver to help develop. It can promote the decomposition of intestinal fat and the absorption of fat soluble vitamins. It can be used for dyspepsia caused by hepatobiliary diseases. It can be used as an anti-inflammatory drug to treat chronic bronchitis and viral respiratory inflammation in children.
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