Wuhan Hhd Supply Pharmaceutical Grade Trans-3-Hydroxy-L-Proline CAS: 4298-08-2

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Transport Package: Drum or as Required
• Specification: Customized
• Trademark: HHD
• Origin: Hubei China
• HS Code: 2933990099
• Production Capacity: 50000 Pieces Per Years

Product Description

Product Description

 

Product Name	TRANS-3-HYDROXY-L-PROLINE
Brand	hhdpharm
CAS No.	4298-08-2
Color	white
Appearance	powder
Storage	At room temperature
MF	C5H9NO3
Shelf Life	2 years
Purity	99%
Grade	Enterprise standard

 

Trans - 3 - Hydroxy - L - Proline (Trans-3Hyp) is a non-proteinogenic amino acid, meaning it is not one of the 20 standard amino acids encoded by the genetic code but plays critical roles in biological systems. It is a hydroxylated derivative of L-proline, where a hydroxyl (-OH) group is attached to the 3rd carbon atom in the trans configuration.

This amino acid is particularly important in collagen biosynthesis, where it contributes to the stability and structural integrity of connective tissues such as skin, bones, tendons, and cartilage. Unlike its cis isomer, trans-3Hyp is the predominant form found in natural collagen, making it essential for proper triple-helix formation and mechanical strength.
 

Key Functions of Trans - 3 - Hydroxy - L - Proline

1. 1.

   Collagen Stabilization

   • Trans-3Hyp is a key post-translational modification in collagen, enhancing the thermal stability and mechanical properties of the collagen triple helix.
   • It forms hydrogen bonds that stabilize the collagen structure, preventing degradation and maintaining tissue elasticity.
2. 2.

   Wound Healing & Tissue Repair

   • Plays a role in fibroblast proliferation and extracellular matrix (ECM) remodeling, aiding in faster recovery from injuries.
3. 3.

   Anti-Aging & Skin Health

   • Supports skin elasticity and hydration, reducing wrinkles and improving skin firmness when used in topical formulations or supplements.
4. 4.

   Bone & Joint Health

   • Contributes to the strength of cartilage, tendons, and ligaments, potentially benefiting conditions like osteoarthritis or joint pain.
5. 5.

   Enzyme Regulation & Metabolic Roles

   • Some enzymes and metabolic pathways utilize hydroxyproline-containing peptides for signaling or structural purposes.

 

Applications in Research & Industry

• Cosmetics: Used in anti-aging creams and serums to boost collagen production.
• Nutraceuticals: Found in supplements targeting joint health and skin regeneration.
• Biomedical Research: Studied for its role in tissue engineering and regenerative medicine.

In summary, Trans - 3 - Hydroxy - L - Proline is a vital amino acid derivative that enhances collagen structure, supports tissue repair, and contributes to overall connective tissue health. Its applications span from medical research to cosmetic and nutritional formulations.

 

 

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