Wuhan Hhd Factory Supply Pharmaceutical CAS 15663-27-1 Cisplatin 99% Anti-Cancer Cisplatin Powder Purity Cisplatin

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• Purity: >98%
• Color: White
• Model NO.: HHD
• Grade: Pharmaceutical Grade
• Usage: Anti-Tumor
• Price: Factory Price
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan hhd factory supply pharmaceutical CAS 15663-27-1 Cisplatin 99% Anti-Cancer Cisplatin Powder Purity Cisplatin

 

Product Name	Cisplatin
CAS	15663-27-1
Appearance	orange yellow powder
Molecular formula	Cl2H6N2Pt
Molecular Weight	300.05
Assay	98%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

Cisplatin bright yellow to orange-yellow crystalline powder; odorless. This product is easily soluble in dimethyl sulfoxide, slightly soluble in dimethyl formamide, slightly soluble in water, and insoluble in ethanol. Cisplatin, also known as cis-dichlorodiammine platinum, is a platinum-containing anticancer drug, orange-yellow or yellow crystalline powder, slightly soluble in water, easily soluble in dimethylformamide, in aqueous solution. can be gradually converted into trans and hydrolyzed. Clinically, it can show curative effect on various solid tumors such as ovarian cancer, prostate cancer, testicular cancer, lung cancer, nasopharyngeal cancer, esophageal cancer, malignant lymphoma, head and neck squamous cell carcinoma, thyroid cancer and osteosarcoma.

Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The compound has also been shown to induce apoptosis through caspase-3 activation and XIAP expression. Also shown to cause immunosuppression which is thought to be followed by an increase in the host immune response. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I by camptothecin (sc-200871). Cisplatin was the first member of a class of anticancer drugs, which now include carboplatin (sc-202093) and oxaliplatin (sc-202270), that form DNA adducts resulting in apoptosis; however, these molecules also bind other biological molecules such as enzymes which might play a role in their mechanism of action.

Cisplatin, cisplatinum, or cis-diamminedichloroplatinum(II)  is a platinum-based chemotherapydrug used to treat various types of cancers, including sarcomas, somecarcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, andgerm cell tumors.
It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis (programmed cell death).
 

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