Wuhan Hhd Supply Pharmaceutical Anticancer Larotrectinib CAS 1223403-58-4 Loxo-101

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Certification: Enterprise Standards
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Color: White
• Grade: Pharmaceutical Grade
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan HHD Supply Pharmaceutical Anticancer Larotrectinib CAS 1223403-58-4 Loxo-101

Product Name	Larotrectinib (LOXO-101)
CAS	1223403-58-4
Appearance	White powder
MF	C21H22F2N6O2
MW	428.44

Larotrectinib (LOXO-101) is an orally administered, small molecule, highly-selective, tropomyosin receptor kinase (TRK) inhibitor which used as a treatment for adult and paediatric patients whose cancers harbour neurotrophic receptor tyrosine kinase (NTRK) gene fusions.

Larotrectinib (LOXO-101) is a highly selective, potent inhibitor of TRKA, TRKB and TRKC with minimal or no activity against other kinase and non-kinase targets.  Inhibition of TRKs prevents TRK activation, resulting in both the induction of cellular apoptosis and the inhibition of cell growth in tumours that overexpress TRKs.