| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Trans ISRIB (integrated stress response inhibitor) as a drug, imparts resistance to the cells against the downstream effects of eukaryotic initiation factor 2 (eIF2)α phosphorylation such as activating transcription factor 4 (ATF4) and eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) induction.
Trans ISRIB is a blood- brain barrier penetrant, potent and selective inhibitor of integrated stress response (ISR) that impairs adaptation to ER stress. Trans ISRIB is a potent inhibitor of PERK signaling, which potently reverses the effects of eIF2a phosphorylation and restores the cells translation capacity. Trans ISRIB enhances cognitive memory in rodents.
Trans ISRIB (integrated stress response inhibitor) has been used as an inhibitor of integrated stress response.
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Product name
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Trans ISRIB
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CAS No.
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1597403-47-8
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Other Names
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ISRIB
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MF
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C22H24CI2N2O4
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EINECS No.
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N/A
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Place of Origin
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China
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Type
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Pharmaceutical Intermediates
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Grade Standard
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Medicine Grade
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Brand Name
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GREENYO
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Purity
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99%min HPLC
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Appearance
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White Powder
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Application
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For research, Intermediates
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1. Trans ISRIB powder has vasodilating, blood thinning, and memory-enhancing actions.
2. Trans ISRIB powder acts as a cerebral stimulant and vasodilator.
3. Trans ISRIB powder is used to treat arteriosclerosis.
4. Trans ISRIB powder is very effective in curing dementia caused due to insufficient blood supply to the brain.
5. Trans ISRIB powder interferes with cells' ability to synthesize DNA and RNA.
Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.
Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q3: Is there a discount?
A:Different quantity has different discount.
Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Bitcoin.
Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
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