Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Product introduction:
Product Name | SM04554 |
CAS No | 1360540-81-3 |
M.F. | C18H16O4 |
M.W. | 296.32 |
Grade | Pharmaceutical Grade |
Color | White powder |
Purity | 99% |
Shelf Life | 2 years |
SM04554 is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment.
SM04554 displayed high affinity for the human CRTh2 receptor (1.14 ± 0.44 nM) expressed in Chinese hamster ovary cells, the binding being reversible and competitive with the native agonist prostaglandin D2(PGD2). SM 04554 was also a potent inhibitor of PGD2-induced cytokine release in human Th2 cells.
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