Wuhan Hhd Supply Pharmaceutical Grade Valaciclovir HCl Antiviral Valaciclovir Hydrochloride Purity Valaciclovir

• Powder: Yes
• Customized: Non-Customized
• Certification: Enterprise Standards
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Model NO.: Valaciclovir Hydrochloride
• Color: White
• Grade: Pharmaceutical Grade
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan HHD Pharm Supply High Quality Antiviral Raw Material Ganciclovir Powder CAS 82410-32-0

product name	Vidarabine
cas number	124832-26-4
apperance	White powder
Density	1.5±0.1 g/cm3
MF	C13H20N6O4
MW	324.336

 

 

Valacyclovir (Valacyclovir) is a guanine analogue antiviral drug, which is clinically used for the treatment of herpes simplex and herpes zoster infections. It is a prodrug of acyclovir and can be converted into acyclovir in the body.

Valacyclovir hydrochloride, an orally active L-valyl ester of the potent antiviral agent aciclovir, was launched in 1995 in the United Kingdom for the treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes, including initial and recurrent enital herpes. As a prodrug, valaciclovir has an improved pharmacokinetic profile to aciclovir. It is rapidly absorbed after oral administration and extensively converted to aciclovir via first-pass metabolism to achieve plasma levels of aciclovir comparable to those seen with aciclovir via i.v. route. Valacyclovir is then activated selectively in virus-infected cells by viral thymidine kinase to form aciclovir triphosphate in a stepwise fashion. This active species inhibits viral DNA polymerase via irreversible binding to the active site of the enzyme. Once aciclovir is incorporated into the elongating viral DNA, it terminates replication of the viral DNA strand, an antiviral mechanism unique to aciclovir. Valacyclovir is reportedly in clinical trials for the suppression of cytomegalovirus infection and disease in renal transplant patients.