HHD high quality Ostase/Alkaline Phosphatase(AP/ALP) CAS 9001-78-9
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(HHDPHARM)
Alkaline phosphatase (ALP) is a homodimeric protein enzyme. Each monomer consists of five cysteine residues, two zinc atoms, and one magnesium atom which is essential to its catalytic function. It performs its optimal activity when in alkaline pH conditions. ALP plays a role in dephosphorylating of compounds. The enzyme is found in a wide range of species including prokaryotes and eukaryotes alike. It harbors different structural forms suitable to the environment but possessing the same normal function. ALP is found in the periplasmic space of E. coli bacteria. This enzyme has thermal stability and maximum activity at high pH. In humans, it is identified in many forms according to its origin within the body. It is involved in the metabolism within the liver and development within the skeleton. Because of it widely ex in different areas, its concentration in the bloodstream is used as a biomarker in helping determine diagnoses such as hepatitis or osteomalacia.
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