Factory Supply Darolutamide ODM-201 ODM201 ODM 201 Anti Hair Loss Darolutamide Power

• Powder: Yes
• Customized: Non-Customized
• Suitable for: Adult
• Purity: >98%
• Color: White
• Grade: Pharmaceutical Grade
• Model NO.: CAS 1297538-32-9
• Transport Package: Alumininum Foli Bags
• Specification: 10g, 50g, 200g, 1kg, 5kg
• Trademark: hhdpharm
• Origin: China

Product Description

Wuhan HHD Supply Darolutamide ODM-201 ODM201 ODM 201 Anti Hair Loss Darolutamide Power CAS 1297538-32-9

 

Basic information:

 

Product Name	Darolutamide
Purity	99%
CAS No.	1297538-32-9
Molecular Formula	C19H19ClN6O2
Molecular Weight	398.85
Appearance	white powder
Shelf life	24 months under the previously mentioned conditions.
Storage	Store in a cool dry place, avoiding sunlight directly.

Description:

ODM-201, also known as Darolutamide, is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509. Importantly, ODM-201 also blocks the activity of the tested mutant ARs arising in response to antiandrogen therapies, including the F876L mutation that confers resistance to enzalutamide and ARN-509. In addition, ODM-201 reduces the growth of AR-overexpressing VCaP prostate cancer cells both in vitro and in a castration-resistant VCaP xenograft model. ODM-201 overcomes resistance to AR-targeted therapies by antagonizing both overexpressed and mutated ARs. ODM-201 is currently in a phase 3 trial in CRPC.