| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Meloxicam, a non-steroidal anti-inflammatory agent, has been reported to inhibit the inducible isoform of Cox-2. Meloxicam is an inhibitor selective for Cox-2 (IC50 of 4.7 μM) over Cox-1 (IC50 of 36.6 μM). Studies suggest that Meloxicam is Cox-2 preferential,therefore it will probably not display a lower gastrointestinal toxicity than non-selective anti-inflammatory agents. This compound has been shown to also inhibit prostanoid synthesis in inflammatory cells. Additionally, Meloxicam has demonstrated the ability to non-competitively inhibit erythrocyte PGD (6-phosphogluconate dehydrogenase) activity in vitro.
Function
Meloxicam is a non-steroidal antipyretic and analgesic anti-inflammatory drug which is not a hormone drug and has strong anti-inflammatory, analgesic and antipyretic effects and can selectively inhibit cyclooxygenase-2 (COX-2) Activity, thereby blocking the synthesis of prostaglandins, the prostaglandin biosynthesis at the inflammatory site is more potent than the prostaglandin biosynthesis of the gastric mucosa or kidney, and is more secure than other NSAIDs. Meloxicam mainly is used to relieve the symptoms of osteoarthritis, painful osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Application
Meloxicam is suitable for treating the symptoms of rheumatoid arthritis, osteoarthritis pain(joint disease, degenerative joint disease) symptoms treatment .
| Name | CAS | molecular | density |
| Meloxicam | 71125-38-7 | C14H13N3O4S2 | 1.613 |
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