Herbal Medicine Cnidium Monnieri Extract 98% Osthole CAS. 484-12-8 Chemcials

• Customization: Available
• Powder: Yes
• Customized: Customized
• Certification: ISO 9001
• Suitable for: Elderly
• State: Solid
• Purity: >99%
• Transport Package: Al-Foil Bag
• Specification: 1bags
• Trademark: HHD
• Origin: China
• Production Capacity: 1000bags

Product Description

Product Description

Herbal Medicine Cnidium Monnieri Extract 98% Osthole CAS. 484-12-8

Product Name	Cnidium monnieri Extract Osthole
Exterior	White, light yellow, brownish yellow powder
Active Ingredient	Osthole 10%, 50%, 90%, 98%
Test Method	HPLC
Extraction Solvent	Ethanol
CAS NO	482-12-8
Molecular Formula	C15H16O3
Molecular Weight	244.29

 

What is Cnidium Monnieri?
Fructus cnidii (Common Cnidium) is annual herb,height 30-80cm. Fructus cnidii leaf is alternate,
compundumbel inflorescence.Cremocarp, ellipsoidal, 2-4 mm long, about 2 mm in diameter. Externally
greyish-yellow or greyish-brown; with 2outcurved stylopods at the summit, and sometimes with a fine fruit
stalk at the base. Dorsal surface of mericarps with five thin and longitudinal ridges, commissural surface
flattened, with two brown and slightly raised longitudinal ribs. Fructus cnidii's pericarp lax and fragile, easily
rubbed off, seed small, greyish-brown and oily. Odour, aromatic; taste, pungent, cool and numb.

Specifiaction: 
Osthole 10% 50% 90% 98% With Pharmaceutical Grade For Health supplement

Osthole 10% Brown green powder
Osthole 50% Yellow green powder
Osthole 90% White powder
Osthole 98% White crystalline powder

Health Benefits of Osthole:

1. Skin Health
The herb's antibacterial, antifungal and antipruritic properties make cnidium ideal for skin treatments. Holistic
practitioners use the extract for numerous skin conditions including dermatitis, eczema, ringworm, rash and itching.

2. Men's Health
>Skeletal Muscle
Osthole has been implicated in increasing AMPK-mediated glucose uptake into myocytes (both C2C12 and L6) in
dose and time dependent manners, although tested mostly at 12.5-50uM and also affects hepatocytes to a less
potent extent. 
Osthole apparently may also phosphorylate (activate) Akt, and the downstream proteins of AS160 and GSK3; another
mechanism by which GLUT4 may be increased.

> Erections
Cnidium Monnieri is, supposedly, a frequently prescribed herb among Chinese Medicine practitioners for male
impotence. It has traditionally been used for treatment of male erections (or the lack thereof) alongside Epimedium
Sagittatum (related to Horny Goat Wee) and the plant Semen Cuscutae.
There may also be central (brain) effects as well, due to the ability of osthole to induce glutaminergic neurotransmission
(see Neurology section).

3.Liver Interactions
>Fatty Liver
Osthole is able to reduce fatty liver induced by Alcohol.

Other
Bodybuilders take cnidium supplements to increase energy and boost athletic performance. Because it improves
concentration and memory, the herb is sometimes used to prevent Alzheimer's disease and other dementias. It is
also beneficial for the weak, brittle bones of osteoporosis.

Applications of Osthole:

Skin care products and cosmetics
It can inhibit the formation of various inflammatory factors and has a good therapeutic effect on facial acne
and acne.For allergic skin diseases, such as eczema, urticaria has a good effect, can be used in anti - allergic
cosmetics.

Dermatological drugs
Osthole has antispasmodic, antihypertensive, antiarrhythmic, immune function and broad-spectrum antibacterial
effects. It has strong pharmacological activity and is an effective pharmaceutical ingredient that can be used in
the pharmaceutical industry.

Pesticides and pesticides
As a new type of biological pesticide, it can inhibit pests and plant pathogens. It is an effective botanical insecticide.

Functions of Osthole:

Antiarrhythmic effect
Water extract and total coumadin from fructus cnidium have obvious preventive effects on chlorofor induced
ventricular fibrillation in mice and calcium chloride induced ventricular fibrillation in rats. Fructus cnidium and
zanthoxylum acetaminophen also have this pharmacological effect and can improve ventricular electrofibrillation
threshold in rabbits. The water extract, total coumarin, cnidium, and phenos of zanthoxylum had significant inhibitory
effects on the flow of sodium ions in the myocardial cell membrane.
 
Antihypertensive, inhibition of vascular dilatation
Osthol had a dose-dependent negative inotropic effect on the left atrium of isolated guinea pigs and a negative
frequency effect on the left atrium of isolated guinea pigs. In addition to the polarization induced by norepinephrine,
CaCl2 and high K+, the aorta contraction dose-response curve of rabbits was shifted to the right and the maximum
response was decreased, indicating the role of biosynthetic compound in relaxing vascular smooth muscle. Fructus
cnidium has a certain antihypertensive effect.

Effects on respiratory system
Cnidium monnieri total coumarin with relaxation by drugs (histamine and acetylcholine) caused by bronchial spasms
and diastole bronchus role directly, this function can be B - adrenalie receptor blockers block by propranolo, mice
after total coumarin cnidium monnieri, obviously increase the amount of pheno red drain in the body, shows strong
expectoranting action.

Anti-inflammatory effects
Cnidium cnidium and phenoic zanthoxylum could inhibit the ear shell swelling of mice caused by xylene and the
increase of capillary permeability in abdominal cavity caused by acetic acid. Osthol and acetonol had significant
inhibitory effects on foot swelling in rats and rats with bilateral adrenal resection. Osthol could also reduce the PGE
content in the inflammatory tissues of the swollen part of the foot in rats, but osthol did not affect the PGE content in
the inflammatory tissues of the swollen part of the foot in rats.

Effects on the nervous system
The total coumarin of cnidium cnidium has an inhibitory effect on central nervous system. Osthol can significantly
enhance the hypnotic effect of pentobarbita sodium on subthreshold hypnotic dose in mice, and this hypnotic effect
is dose-related. Cnidium cnidium can promote the learning and memory of mice, and significantly improve the memory
acquisition, consolidation and direction discrimination of mice.

Anti - mutagenesis, anti - cancer effect
Cnidium, parsley b, bergamot lactone, isorhein, zanthoxylum acetaminophen and zanthoxylum toxin have high activity
in inhibiting the mutagenesis of aflatoxin B1. Water extract of cnidium could inhibit S130 sarcoma, prolong survival days
and inhibit tumor growth.



Package:1kg/aluminum foil bag;25Kgs in fiber-drums with two-plastic bags inside
Net Weight:25kgs/Drum/Gross Weight:28kgs/Drum
Drum Size & Volume:I.D.42cm × H52cm,0.57m³/Drum

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