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Wuhan HengHeDa Pharm Co., Ltd.

Nmda, Sport Nutrition, 6384-92-5 manufacturer / supplier in China, offering High Quality N-Methyl-D-Aspartic Acid CAS: 6384-92-5, Azilsartan Kamedoxomil CAS863031-24-7pharmaceutical Grade Research Chemicals, Benzarone CAS1477-19-6 Pharmaceutical Grade Research Chemicals and so on.

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Supplier Homepage Product Pharmaceutical Intermediates High Quality N-Methyl-D-Aspartic Acid CAS: 6384-92-5

High Quality N-Methyl-D-Aspartic Acid CAS: 6384-92-5

FOB Price: US $1-2 / Piece
Min. Order: 100 Pieces
Min. Order FOB Price
100 Pieces US $1-2/ Piece
Get Latest Price
Production Capacity: 1000/Kg Per Month
Transport Package: Alumininum Foli Bags
Payment Terms: T/T, Western Union, Money Gram

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Basic Info
  • Model NO.: HHD-NMDA
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Grade: Pharmaceutical Grade
  • Place of Origin: Wuhan, China
  • Target Market: Worldwide
  • Stability: Stable
  • Stock Availability: Large Stock
  • Specification: 1KG/bag
  • HS Code: 3001200010
  • Powder: Yes
  • Certification: USP, Enterprise Standards
  • State: Powder
  • Color: White
  • Standard: USP/ Bp / Cp
  • Application: Pharmaceutical Raw Intermediates
  • Assay Test Method: HPLC / UV
  • Shelf Life: 2 Years with Proper Storage
  • Trademark: hhdpharm
  • Origin: China
Product Description
Introduction:
Name:N-Methyl-D-aspartic acid
 CAS No.: 6384-92-5
 Molecular formular:C5H9NO4
Details of N-Methyl-D-aspartic acid
Superlist Name:N-Methyl-D-aspartic acid(NMDA)
 
Molecular Formula:C5H9NO4
 
CAS No.: 6384-92-5
 
Purity:99%
 
Synonyms:(R)-2-(Methylamino)succinic acid; NMDA
 
Molecular Weight:147.13
 
Appearance:white powder
 
Function :
 
N-Methyl-D-Aspartic acid (NMDA) is a water-soluble synthetic substance that is  not normally found in biological tissue. It was first synthesized in 1960s. N-Methyl-D-Aspartic acid (NMDA) is an excitotoxin(it kills nerve cells by over-exciting them);  this trait has applications in behavioral neuroscience research. The body of work utilizing this technique falls under the term "lesion studies."  
 
Researchers apply N-Methyl-D-Aspartic acid (NMDA) to specific regions of an  (animal) subject's  brain  or spinal cord and subsequently test for the behavior of  interest,  such as operant behavior. If the behavior is compromised, itsuggests  the destroyed tissue was part of a brain region that made an important contribution to the normal expression of that behavior. 
 
However, in lower quantities N-Methyl-D-Aspartic acid (NMDA) is not neurotoxic.  
 
In  fact, normal operation of the N-Methyl-D-Aspartic acid (NMDA)  receptor allows  individuals to respond to excitatory stimuli through the interrelated functioning of N-Methyl-D-Aspartic acid (NMDA) receptors, glutamate, and dopamine. 
 
Therefore the action of glutamate specifically through N-Methyl-D-Aspartic acid  (NMDA) receptors can be investigated by injecting small quantities of N-Methyl-D-Aspartic acid (NMDA) into a certain region in the brain: for example, injection of N-Methyl-D-Aspartic acid (NMDA) in a brainstem region induces  involuntarylocomotion in cats and rats. 
 
The mechanism of stimulating N-Methyl-D-Aspartic acid (NMDA) receptor is a  specific agonist-binding to its NR2 subunits, and then a non-specific cation  channel is opened, which can allow the passage of Ca2+ and Na+ into the cell and K+ out of the cell. The excitatory postsynaptic potential (EPSP) produced by activation of an N-Methyl-D-Aspartic acid (NMDA) receptor  also increases  the  concentration of Ca2+ in the cell. The Ca2+ can in turn function as a second messenger in various signaling pathways.This process is modulated by a number of endogenous and exogenous compounds and play a key role in a wide range of physiological (e.g. memory) and pathological processes (e.g. excitotoxicity). 
 
It has been deemed responsible for the incredible increase of hormonal output experienced during puberty, which results in rapid muscular and sexual development. This hormonal state is most desirable for building muscle mass and even useful in enhancing every aspect of sexual performance. This newly found receptor, when powerfully activated by amino acid based ingredient called N-Methyl-D-Aspartic acid (NMDA), elicits profound  elevations of circulating anabolic hormones.There are studies showing it increases LH and test levels. N-Methyl-D-Aspartic  acid (NMDA) receptor activation also plays a role in developing many neuro-degerative disorder like Parkinsons.
 
ITEMSPECIFICATIONRESULT
Description:
  Appearance

White or almost white crystalline powder
 
Complies
Tests:
  Identification
 
 
 
  Identification
 
 
  Identification
  Melting Point
  Clarification degree of solution  
  Solution color
  Residue on ignition
  Loss on drying
  Heavy metals(as Pb)
PH
 
Infrared absorption spectrum conformity
 
 
 
 
Conform to Reference substance solutions
 
 
Positive reaction
151ºC~154ºC
≤1 turbidity standard fluid
Colourless
0.1%max
0.5%max
<10ppm
5.0~7.0
 
Infrared absorption spectrum conformity with Comparison spectrum
Reference substance solutions
 
Peak's retention time conformity with peak of reference substance solutions
 
Positive reaction
152.2~153.4ºC
≤1 turbidity standard fluid
Colourless
0.03%
0.26%
<10ppm
6.53  

 
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