Tianeptine Sulphate vs Tianeptine Sodium
What's the difference between tianeptine sulphate vs tianeptine sodium?
Apart from the obvious chemical difference (discussed above), the significant differences are:
- Stability. Tianeptine sodium is unstable and decomposition occurs in the presence of light, heat and moisture. Tianeptine sulphate appears to be more stable.
- Half-life. Tianeptine sulphate has a longer duration of action (tianeptine sodium only lasts 2-3 hours; tianeptine sulphate lasts all day).
- Potency. To achieve the same effects, roughly twice the tianeptine sulphate dosage is needed.
- Physical properties. Tianeptine sodium is extremely hygroscopic (it absorbs moisture from air); tianeptine sulphate is not hygroscopic.
- Absorption. In this case, tianeptine sulphate's inefficient absorption and excretion is an asset, because it delays release in a controlled fashion resulting in a longer duration.